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Borrelia burgdorferi, the causative agent of Lyme disease, is known to be able to disseminate and colonize various organs and tissues of its hosts, which is very crucial for its pathogenicity and survival. Recent studies have shown the presence of Borrelial DNA in various kinds of breast cancer tissues with poor prognosis which raises the question about whether B. burgdorferi could play a role in tumor development. In this webinar, recent research data will be discussed on the potential role of B. burgdorferi in breast cancer.