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During this webinar I will highlight the concerns of hormone replacement and the development of breast cancer.  Despite the multiple literature citations describing the benefit of hormone replacement therapy in menopause in terms of cardiac protection, anti-inflammatory effects, neuroprotection and more there still exits a concern in the community of patients about the safety of hormones in terms of breast cancer.  The microbiome plays a major role in the offload of estrogen metabolites and the overall detoxification process.  The webinar will discuss the recent literature evaluations of the old hormone replacement studies and what we can do to maximize prevention. Recent research suggests that the microbiota of women with breast cancer differs from that of healthy women.  This concept that certain bacteria may be associated with cancer development is an extremely important concept.  It will enable us to use testing and nutrition to maximize the gut health of postmenopausal women while minimizing risk of breast malignancy.