Oncogenic Epigenetic Alterations and the 3D Organization of Chromatin

Arima Genomics
10/28/21, 12:00 PM
America/Pacific Time UTC -8:00 / -7:00

Description

Understanding cancer — understanding chromatin architecture
Cancer often exhibits multiple genetic, epigenetic, and chromosomal alterations. To elucidate the underlying complexities, oncology research focused on noncoding regions of the genome has revealed many new mechanisms affecting oncogene expression. Join our webinar to hear Dr. Elisa Oricchio share her work to better understand cancer through 3D chromatin architecture.

Join this webinar to hear Dr. Elisa Oricchio discuss her recent findings and learn how:

  • Chromosomal alterations including enhancer hijacking and epigenetic changes lead to modifications of the chromatin architecture in lymphoma
  • Epigenetic markers modulate chromatin interactions between regulatory elements to support transcriptional oncogenic programs
  • Chromosomal translocation and epigenetic changes can induce allele-specific chromatin configurations supporting monoallelic oncogene expression
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Oncogenic Epigenetic Alterations and the 3D Organization of Chromatin

Inglês

 

Speakers

Elisa Oricchio